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EWMA2017 Amsterdam - KADERMIN NPL

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EWMA2017 Amsterdam - KADERMIN NPL

Uploaded by

edo adimasta
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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European Wound Management Association

27th European Conference - Amsterdam (The Netherlands)


ICCS
3-5 May 2017
Ionic silver powder to control
proliferation of neoplastic skin lesions
R.Cassino
“Città Studi” Clinical Institute - Milan (Italy)
Diabetic Foot and Vulnology Treatment & Research Center

INTRODUCTION AND AIM


This work is a challenge against the wounds that cannot heal
without a surgical solution: the neoplastic ulcers. Especially in
elderly people we try to avoid surgery, if possible; so we need a
local treatment that tries to stop or slow proliferation, that can
reduce infectious complication and bleeding and help
epithelialization.
ICCS MATERIALS AND METHODS
10 patients have been involved and terminated
the observational time of 4 weeks; 7 of them
achieved the end of follow up (12 months). We
treated the wounds with a daily application of a
spray powder containing silicon dioxide, ionic
silver and chlorhexidine (SiO2-Ag+Chlorex)*;
non-adherent secondary dressing.
After 4 weeks we evaluated wound area,
infection signs and bleedings.
Monthly follow up for 12 months.

*KAdermin Spray Powder (Pharmaday Pharmaceutical)


RESULTS / DISCUSSION
ICCS
After 4 weeks we had no area change in 6
patients, a light reduction in 3 and a complete
epithelialization in 1; no infections and only one
bleeding, fully controlled with an alginate
dressing for 24 hours. Actually no relapses, no
worsening, no infections, two bleedings (the
same patient) and 4 complete epithelialization.

15 days later
Patients 1 2 3 4 5 6 7 8 9 10
FOUR WEEKS FOLLOW UP
ICCS Wound Area n.c. -14% n.c. n.c. n.c. Epith. n.c. -33% -37% n.c.
Infection --- --- --- --- --- --- --- --- --- ---
Bleeding --- --- --- X --- --- --- --- --- ---
TWELVE MONTHS FOLLOW UP
Wound Area -29% Epith. -39% -7% n.c. Epith. -48% Epith. Epith. n.c.
Infection --- --- --- --- --- --- --- --- --- ---
Bleeding --- --- --- X (2) --- --- --- --- --- ---

Wound Area Reduction: 4/10 - Epithelialization: 4/10 - Bleeding: 1/10 - Infection: 0/10
NO INDUCED PAIN

CONCLUSION
We all know that no dressing can heal a neoplastic
lesion, but in case of non surgical treatment we can
help patients reducing complications and giving a
satisfactory quality of life.

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