Reference Design Tinnitus No.

of Control Group Intervention Outcome Statistical

Fukuda, S., RCT Adult patients n=23 The patients were TRT performed by THI, THQ, TSI Student’s TRT usin
Miyashita, T., with chronic divided into the using a portable unpaired t-tests similar to
Inamoto, R., & tinnitus PMP (portable music player The THI scores were used to The murm
Mori, N. (2011). music player) group, (PMP) with were evaluated determine of the mo
Tinnitus retraining TCI (tinnitus control recorded before treatment statistical TRT. TRT
therapy using instrument) group, environmental and 1 month, 3 differences at P sound ge
portable music and HA (hearing sounds as the months, 6 months, values less most cos
players. Auris aid) group sound generator, and 12 months than 0.05. option for
Nasus Larynx, after treatment.
38(6), 692-696.

Atipas, S., RCT Thai patients n=104 2 groups: a The treatment THI and total VAS Chi-square The dem
Therdphaothai, J., with chronic treatment group group received score tests, linear groups sh
Suvansit, K., tinnitus (listening to tailor- TMNMT (tailor- mixed model significan
Prakairungthong, made notched made notched Follow-up for THI and Tinnitus H
S., Thongyai, K., & music) and a control music therapy) assessments at 1, VAS the total V
Limviriyakul, S. group (listening to while the control 3, and 6 months demonstr
(2021). A ordinary music) group received after the difference
randomized, ordinary music participants started treatmen
controlled trial of (original songs listening to the reduction
notched music without music control gr
therapy for tinnitus modification) period.
patients. J Int Adv therapy
Otol, 17(3), 221-
227.

Simonetti, P., RCT Brazilian n=12 No control group The fractal tones At Paired sample The mea
Vasconcelos, L., & patients with were delivered baseline and at 1, t-test baseline
Oiticica, J. (2018). chronic using behind-the 3 and 6 months, was 25. A
Effect of Fractal tinnitus ear hearing aids the participants showed t
Tones on the (Widex, Lynge, were provided with difference
Improvement of Denmark). All the Tinnitus significan
Tinnitus Handicap participants Handicap Inventory bothersom
Inventory were fitted with the (THI) and Hearing high scor
Functional Scores devices in both Handicap Inventory scale, fra
among Chronic ears, and all wore for Adults (HHIA) considere
Tinnitus Patients: them as questionnaires. initial sou
An Open-label open fittings.
Pilot Study.
International
Archives of
Otorhinolaryngolog
y. doi:10.1055/s-
0038-1635575

Diao, M., Tian, R., RCT Chinese n=70, Two groups : the The subjects were Before and after Chi-square After 3 m
Tian, F., Lin, X., & patients with Seventy control group and instructed to listen 3 months of test. An subjects
Sun, J. (2020). chronic participants the treatment group to music treatment , THI and independent showed s
Analysis of the idiopathic completed at a ratio of 1:2. The with a comfortable VAS were samples t reduction
effects and tinnitus the study control group intensity in a quiet assessed . test was used compared
predictors of tailor- (control was given the environment. The to analyse the
made notched group original music cumulative daily variance
music therapy for n=21,treatme without any listening time was homogeneity of
chronic idiopathic nt group modification; the at least two hours, the data.
tinnitus patients: n=49) treatment group was and a single Logistic
our experience given treatment episode regression
with 70 patients. tailor-made notched lasted for three multivariate
Clinical music. consecutive analysis was
Otolaryngology: months. used to analyse
Official Journal of the predictive
ENT-UK; Official factors in the
Journal of treatment
Netherlands group. A
Society for Oto- two-tailed p
Rhino-Laryngology value less than
& Cervico-Facial 0.05 indicated
Surgery. statistical
significance.

Yoo, S., Yakunina, RCT Adult Korean n=100, Control group The participants The Tinnitus Mann–Whitney All measu
N., & Nam, E. C. patients with 41 and 33 listened to music provided audio Handicap Inventory U-test and chi- showed s
(2022). Does chronic continuing for stripped of a files of their (THI) score and square test. both grou
Listening to tonal/narrowb 3 months, random frequency favourite music, measures of The amounts of tinnitus lo
Tinnitus and tinnitus > and 14 and unrelated to the which we modified tinnitus loudness, improvement at minimal m
Frequency-Filtered 3 months 15 continuing tinnitus pitch and according to the daily awareness, 3 and 6 months no signifi
Music Relieve for 6 months, treatment group group allocation and tinnitus- were compared difference
Tinnitus?. Korean in the listened to tinnitus and then uploaded induced annoyance between the amount o
Journal of experimental frequency-filtered to their were evaluated at two groups scores an
Audiology. and control music. smartphones. The the initial visit and using the The rates
groups, participants were at 3 and 6 months paired t-test. THI score
respectively instructed to listen (final follow-up). p<0.05 was control gr
to the modified The rates of accepted as
music files for 2 h improvement in the statistical
daily for 6 months. THI scores in the significance in
Hearing function two groups were all analyses.
and tinnitus were also recorded.
assessed at
enrolment, and
after 3 and 6
months.

Li, S. A., Bao, L., & Blinded RCT Adult Canadian n=50,treatme Participants were The treatment THI, Tinnitus Linear Data from
Chrostowski, M. patients with nt (n = 25) randomly assigned group received Functional Index regression analyzed
(2016). chronic, and control (n into 2 groups: one classical music (TFI), and Hospital reported
Investigating the unilateral or = 25) group received music that had been Anxiety and of tinnitus
effects of a bilateral tinnitus altered by the modified based on Depression Scale outcome,
personalized, ≥ 12 months software to treat spectral (HADS) were Tinnitus H
spectrally altered tinnitus, and the alterations specific administered. the contro
music-based other received to their tinnitus follow-up
sound therapy on unaltered music. characteristics.
treating tinnitus: a Altered music has Tinnitus and
blinded, been spectrally psychological
randomized altered according to functioning were
controlled trial. each individual’s assessed at
Audiology and tinnitus baseline and 3, 6,
Neurotology, 21(5), characteristics and and 12 months
296-304.plasticity, audiogram. after initial testing
2014. using self-reports.

Mahboubi, H., RCT Adult patients n=23 Subjects were The clinical trial The outcome Mean, standard Customiz
Haidar, Y. M., of the randomized to was designed as a variables were deviation (SD), decrease
Kiumehr, S., Ziai, Veteran’s receive either randomized tinnitus loudness and median scores of
K., & Djalilian, H. hospital in customized sound crossover study (scored 0-10), were calculated results m
R. (2017). California with therapy or with 2 arms. The Tinnitus Handicap for VAS, THI, broadban
Customized versus tinnitus of 3 broadband noise for first arm started Inventory (THI), BAI, BDI, MML,
noncustomized months or 2 hours per day for with 3 months of Beck Anxiety and RI. The
sound therapy for more 3 months and then broadband noise Inventory (BAI), Wilcoxon
treatment of switched to the therapy minimum masking signed-rank
tinnitus: a other treatment after (noncustomized), levels (MML), and test was used
randomized a washout period. and the second residual inhibition to analyze the
crossover clinical arm started with (RI). changes in
trial. Annals of customized sound these variables.
Otology, Rhinology therapy (classical The Mann-
& Laryngology, music with narrow- Whitney U test
126(10), 681-687. band noise peaks was used to
centered on the compare the
pitch-matched changes
frequency in its between
first and fourth customized and
subharmonics) noncustomized
sound
therapies.

Deniz, H., Bayazit, Non- Adult chinese n=67, the Patients with only In EC group Chinese Mandarin T-test and The PMT
Y. A., & Sarac, E. randomized patients with treatment educational (control group), version of Tinnitus ANOVA chronic ti
T. (2021). controlled study chronic group (PMT) counseling (1 hr) patients received Handicap Inventory distress i
Individualized tinnitus > 6 consisted of 1 session of (THI-CM), Tinnitus outperfor
treatment of months 30 tinnitus individualized EC. Evaluation which is a
tinnitus during patients In PMT group Questionnaire option in
sleep using (treatment), (TEQ), and Visual presents
combined tinnitus *Preferred patients received Analogue Scale to the the
signal and music. music 1 session of (VAS) were chronic ti
ORL, 83(1), 35-40. therapy - EC individualized EC administered
(1 hr and 15 preferred before and 1, 2, 3
Educational music sessions weeks after
counseling (PMS), which took initiation of
plus 30 min. place on 15 treatment to
Preferred consecutive evaluate the
music workdays with 1 efficacy.
sessions) PMS per day.
After EC, the 1st
PMS was
implemented
immediately. The
PMS sessions
were assessed
every day for 3
weeks.

Wazen, J. J., Multi- Adults with n=52 No control group NeuromonicsTreat TRQ, THI, HADS Wilcoxon Tinnitus H
Daugherty, J., institutional chronic ment was Patients’ signed rank scores w
Pinsky, K., prospective tinnitus for a delivered in 2 responses were test was used in 77% of
Newman, C. W., open label, minimum of 6 stages: Stage 1 recorded from 38 to evaluate and 50%
Sandridge, S., nonblinded months, with consisted of patients at 6 absolute customiz
Battista, R., ... & case series poor or no stimulation with months, 28 changes and system o
Luxford, W. (2011). study response to the patient- patients at 12 percentage means of
Evaluation of a previous customized months, and 12 changes in patients w
customized treatments, musical tracks and patients at 24 TRQ and THI
acoustical stimulus and not white noise months after scores from the
system in the undergoing masking of the initiation of baseline. The
treatment of concomitant tinnitus for 2 treatment. Cochran-
chronic tinnitus. therapies were months, 2 to 4 Armitage linear
Otology & enrolled. hours a day. trend test was
Neurotology, 32(4), Stage 2 consisted used to
710-716. of listening to the evaluate
same tracks, with whether there
no tinnitus was a linear
masking for 4 trend in the
months. Both proportions of
phases included patients with
education, clinically
cognitive therapy, important
and periodic changes over
follow-up time.

Newman, C. W., & Retrospective 56 Adult n=56, n=33 n=23 patients for The Neuromonics Sound therapy t-tests for Both SGs
Sandridge, S. A. between- patients drawn patients for SG (Sound sound processor benefit was paired significan
(2012). A subject clinical from the NTT generator treatment) (Oasis, quantified using the comparisons tinnitus h
comparison of study Tinnitus (Neuromonic Neuromonics, Tinnitus Handicap were performed being mo
benefit and Management s Tinnitus Inc.) delivers Inventory (THI). to compare patients h
economic value Clinic at the Treatment) music stimuli (four The questionnaire mean THI problems
between two Cleveland music tracks are was administered scores between therapy.
sound therapy Clinic with available to the before and 6 mo treatments at
tinnitus chronic patient—two in the after initiation of baseline and at
management tinnitus with baroque genre tinnitus treatment. 6 mo.
options. Journal of more than 6 and two in the
the American months New Age genre) to
Academy of the patient through
Audiology, 23(02), a set of
126-138. earphones. 6
months of NTT
treatment: 2
months of pre-
conditioning and 4
months of active
treatment.

Sruthi, N., Comparative 90 patients n=90; n=30 n=30 Group B Patients in the Tinnitus Handicap Statistical There is a
Venkataramanuja longitudinal aged 18 years group A. (Pharmacotherapy) music therapy Inventory (THI) and comparison the mean
m, N. C., study and older with Music and n=30 Group C group received Visual Analogue between the and mean
Karthikeyan, P., complaints of Therapy (Tinnitus masker) counselling on the Scores (VAS) were groups was months fo
Kaipuzha, R. R., & chronic first day, followed recorded both prior performed treated w
Pulimoottil, D. T. tinnitus by 50 min-long to and following using Chi- patients w
(2021). A presenting to sessions of therapy, and square analysis outcome
Comparative Study the Outpatient pleasant relaxing patients were for categorical did not re
of Treatment Department of music of the followed up variables and t- treatmen
Outcomes of Music Otorhinolaryng patients’ choice on monthly up to 2 test and
Therapy, Tinnitus ology and alternate days months. ANOVA for
Maskers and Head and from Monday to continuous
Pharmacotherpy in Neck Surgery Saturday, for one variables.
Chronic Subjective month.
Tinnitus. Indian
Journal of
Otolaryngology
and Head & Neck
Surgery, 1-5.

Shabana, M. I., RCT Hearing n=40 40 patients divided n=20. Hearing Final assessment T-test, Counselli
Dabbous, A. O., impaired adult into two groups: aids without zen after 4 months of ANOVA,Post significan
Abdelmajeed, M. subjects with Both received program (Zen regular daily use of Hoc Fisher improvem
A., & Abdelkarim, tinnitus with counselling for 2 tones of fractal the hearing aids, LSD, Kruskal– hearingim
A. M. M. (2018). more than 6 months then music) by THI and TFI Wallis test, combined
Counselling and months amplification for 4 Questionnaires Pearson and ampl
amplification with months. The study (outcome 2): The correlation remarkab
and without fractal group (n=20) had total intervention added mu
music (Zen tones) their hearing aids period was six improvem
for management of with Zen program months for the effective
patients suffering (Zen tones of fractal cases and control perceived
from hearing loss music) activated. groups.
and tinnitus.
Hearing, Balance
and
Communication,
16(1), 41-55.