Anatomy and Physiology of Renal System
Anatomy and Physiology of Renal System
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The Kidneys
The kidneys, which maintain the purity and constancy of our internal fluids, are perfect examples
of homeostatic organs.
● Location. These small, dark red organs with a kidney-bean shape lie against the dorsal
body wall in a retroperitoneal position (beneath the parietal peritoneum) in the superior
● lumbar region; they extend from the T12 to the L3 vertebra, thus they receive protection
from the lower part of the rib cage.
● Positioning. Because it is crowded by the liver, the right kidney is positioned
slightly lower than the left.
● Size. An adult kidney is about 12 cm (5 inches) long, 6 cm (2.5 inches) wide, and 3 cm (1
inch) thick, about the size of a large bar of soap.
● Adrenal gland. Atop each kidney is an adrenal gland, which is part of the endocrine
system and is a distinctly separate organ functionally.
● Fibrous capsule. A transparent fibrous capsule encloses each kidney and gives a fresh
kidney a glistening appearance.
● Perirenal fat capsule. A fatty mass, the perirenal fat capsule, surrounds each kidney and
acts to cushion it against blows.
● Renal fascia. The renal fascia, the outermost capsule, anchors the kidney and helps hold
it in place against the muscles of the trunk wall.
● Renal cortex. The outer region, which is light in color.
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● Renal medulla. Deep to the cortex is a darker, reddish-brown area.
● Renal pyramids. The medulla has many basically triangular regions with a striped
appearance, the renal, or medullary pyramids; the broader base of each pyramid faces
toward the cortex while its tip, the apex, points toward the inner region of the kidney.
● Renal columns. The pyramids are separated by extensions of cortex-like tissue.
● Renal pelvis. Medial to the hilum is a flat, basinlike cavity, which is continuous with the
ureter leaving the hilum.
Nephrons
Nephrons are the structural and functional units of the
kidneys. Each kidney contains over a million tiny structures
called nephrons, and they are responsible for forming urine.
Ureters
The ureters do play an active role in urine transport.
● Size. The ureters are two slender tubes each 25 to 30
cm (10 to 12 inches) long and 6 mm (1/4 inch) in
diameter.
● Location. Each ureter runs behind the peritoneum from the renal hilum to the posterior
aspect of the bladder, which it enters at a slight angle.
● Function. Essentially, the ureters are passageways that carry urine from the kidneys to
the bladder through contraction of the smooth muscle layers in their walls that propel
urine into the bladder by peristalsis and is prevented from flowing back by small valve-
like folds of bladder mucosa that flap over the ureter openings.
Urinary Bladder
The urinary bladder is a smooth, collapsible, muscular sac that stores urine temporarily.
● Location. It is located retroperitoneally in the pelvis just posterior to the symphysis
pubis.
● Function. The detrusor muscles and the transitional epithelium both make the bladder
uniquely suited for its function of urine storage.
● Trigone. The smooth triangular region of the bladder base outlined by these three
openings is called the trigone, where infections tend to persist.
Iloilo Doctors’ College
College of Nursing
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● Detrusor muscles. The bladder wall contains three layers of smooth muscle, collectively
called the detrusor muscle, and its mucosa is a special type of epithelium, transitional
epithelium.
Urethra
The urethra is a thin-walled tube that carries urine by peristalsis from the bladder to the outside
of the body.
● Internal urethral sphincter. At the bladder-urethral junction, a thickening of the smooth
muscle forms the internal urethral sphincter, an involuntary sphincter that keeps the
urethra closed when the urine is not being passed.
● External urethral sphincter. A second sphincter, the external urethral sphincter, is
fashioned by skeletal muscle as the urethra passes through the pelvic floor and
is voluntarily controlled.
● Female urethra. The female urethra is about 3 to 4 cm (1 1/2 inches) long, and its
external orifice, or opening, lies anteriorly to the vaginal opening.
● Male urethra. In me, the urethra is approximately 20 cm (8 inches) long and has three
named regions: the prostatic, membranous, and spongy (penile) urethrae; it opens at the
tip of the penis after traveling down its length.