A Gamer, a Girl, a Mad Scientist and an Alien are all that stands between 6 billion zombies and the world’s supply of delicious, supple brains. All Zombies Must Die! drops up to four players into the town of Deadhill, where they must blast their way through ranks of brain hungry monsters with a variety of weaponry while completing quests served up by the game's insane storyline.

Savvy survivors will utilize a combination of the surrounding environment and improvised weaponry to aid in their fight against an unrelenting army of terrifying, yet funny, zombies. As they progress, players will unlock new weapons, new characters and new arenas as well as the ability to customize both their characters and weapons.