Having defeated the evil ghost pirate LeChuck in his first adventure, pirate extraordinaire Guybrush Threepwood sets his sights on the treasure of Big Whoop. Legendary treasures however, come with legendary challenges and Guybrush will have to use his wits and humor to prove himself the greatest pirate in the Caribbean. Voodoo dolls, spitting contests and amusement parks are just some of the challenges Guybrush must overcome as he meets old friends, fights familiar enemies and uses every single ounce of his wits to become the most celebrated pirate ever.