Reye's and Reye's-like syndromes
- PMID: 18711704
- DOI: 10.1002/cbf.1465
Reye's and Reye's-like syndromes
Abstract
The review reports various questions about Reye's syndrome and Reye's-like syndromes. Although there is a significant decrease in the classic Reye's syndrome cases, because of the reduced employment of salicylates in children (salicylate seems to be the most important inducing factor of the syndrome in paediatric subjects affected by viral infection), the problem is still of interest considering the presence of different Reye's-like forms. All these pathological situations are associated with various aetiologic or predisposing causes that are examined in the text. Particular attention is placed on metabolic disorders, especially of fatty acid metabolism, and also of one amino acid. In fact, a latent form can also be the basis of possible biochemical disturbances induced by various exogenous factors such as viral infections, particularly of the respiratory tract (more rarely of bacterial aetiology), or produced by microbial toxins, or by chemical substances, including some therapeutic drugs. A full discussion of biochemical mechanisms of salicylate-induced Reye's syndrome is reported. Finally a possible diagnostic differentiation from classic Reye's syndrome and Reye's-like syndromes plus therapeutic prospects are briefly examined.
Copyright (c) 2008 John Wiley & Sons, Ltd.
Similar articles
-
Reye's syndrome. A review from the forensic viewpoint.Am J Forensic Med Pathol. 1983 Dec;4(4):323-9. Am J Forensic Med Pathol. 1983. PMID: 6364791 Review.
-
Reye's syndrome in the United States from 1981 through 1997.N Engl J Med. 1999 May 6;340(18):1377-82. doi: 10.1056/NEJM199905063401801. N Engl J Med. 1999. PMID: 10228187
-
[Reye's syndrome. Clinical and etiopathogenetic aspects. Case contribution].Pediatr Med Chir. 1987 Jan-Feb;9(1):49-54. Pediatr Med Chir. 1987. PMID: 3628052 Italian.
-
[Reye syndrome].Monatsschr Kinderheilkd. 1987 Oct;135(10):699-704. Monatsschr Kinderheilkd. 1987. PMID: 3317005 Review. German.
-
Is aspirin a cause of Reye's syndrome? A case against.Drug Saf. 2002;25(4):225-31. doi: 10.2165/00002018-200225040-00001. Drug Saf. 2002. PMID: 11994026
Cited by
-
Atypical Reye syndrome: three cases of a problem that pediatricians should consider and remember.Acta Biomed. 2021 Apr 30;92(S1):e2021110. doi: 10.23750/abm.v92iS1.10205. Acta Biomed. 2021. PMID: 33944820 Free PMC article.
-
The intersection of influenza infection and autoimmunity.Front Immunol. 2025 Apr 3;16:1558386. doi: 10.3389/fimmu.2025.1558386. eCollection 2025. Front Immunol. 2025. PMID: 40248710 Free PMC article. Review.
-
Newly Approved Agents for the Treatment and Prevention of Pediatric Migraine.CNS Drugs. 2016 Sep;30(9):837-44. doi: 10.1007/s40263-016-0375-y. CNS Drugs. 2016. PMID: 27503180 Review.
-
Neurologic Manifestations of the World Health Organization's List of Pandemic and Epidemic Diseases.Front Neurol. 2021 Feb 22;12:634827. doi: 10.3389/fneur.2021.634827. eCollection 2021. Front Neurol. 2021. PMID: 33692745 Free PMC article. Review.
-
Microvesicular Steatosis and Severe Cardiac Allograft Dysfunction.Transplant Direct. 2022 Feb 10;8(3):e1290. doi: 10.1097/TXD.0000000000001290. eCollection 2022 Mar. Transplant Direct. 2022. PMID: 35187215 Free PMC article. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
